ORPHEUS runs thematic conferences annually, addressing key topics in graduate research of interest to its network. In cooperation with the Association of Medical Schools in Europe (AMSE) and the World Federation for Medical Education (WFME), ORPHEUS has developed Best Practices for PhD Training.

Graduate schools can measure their practices in PhD training against these tenets and ORPHEUS offers support and guidance in the pursuit of certification and labelling as quality assurance mechanisms. ORPHEUS also offers disciplinary-specific training opportunities for research students and supports the professional development of new and experienced research supervisors.